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以下資料來源: http://www.symbyax.com/Pages/understanding-bipolar-depression.aspx
What Is Bipolar I Depression?

Bipolar I depression is just one phase of bipolar I disorder, an illness that affects millions of people.

Most people experience changes in their mood and feelings as part of everyday life. For people with bipolar I disorder, these changes are much more dramatic.

No one really knows what causes bipolar I disorder. One common theory is that the condition could be caused by a variety of factors, which can include an individual's genes, his or her environment, and brain chemical imbalances. It's important to remember that bipolar I disorder is an illness. If you have the condition, you didn't do anything to cause it and you can't just "snap out of it."

To help identify if you could have bipolar I depression or be having a relapse of the condition, it's important to be able to recognize its symptoms. Learn more about the manic and depressive symptoms of bipolar I depression.

Symbyax is approved for acute treatment of bipolar I depression in adults. Symbyax is not approved for the treatment of bipolar I mania.

Bipolar I Depression Symptoms

The two phases of bipolar I disorder, mania and depression, have their own sets of symptoms; however, some people may have a mixed episode in which they have manic and depressive symptoms at the same time. The severity of the symptoms varies from person to person and from episode to episode.

Recognizing depression and mania symptoms can play an important role in identifying and diagnosing acute bipolar I disorder.

Symptoms of Bipolar I Depression

If you have a major depressive episode, that means you must have experienced either extreme sadness or numbness almost all day, every day, for at least 2 weeks.

Additionally, you should show signs of at least four of the following symptoms almost every day:

Significant changes in appetite and/or weight (eg, may crave specific foods or be unable to eat)
Sleep problems (eg, may have insomnia or sleep too much)
Loss of energy or fatigue (eg, may take much longer to do simple, everyday tasks)
Trouble concentrating (eg, may have a hard time making decisions or focusing on work)
Slowed speech, thinking or body movements (eg, may take a long time to answer a question)
Inappropriate feelings of guilt or worthlessness (eg, may fixate on perceived failings)
Agitation or restlessness (eg, may not be able to sit still)
Recurring thoughts of death or suicide (eg, may have plans for how to commit suicide)

Symptoms of Bipolar I Mania

Note: Symbyax is approved for acute treatment of bipolar I depression in adults. Symbyax is not approved for the treatment of bipolar I mania. The following information is provided for information purposes only.

The main feature of a manic episode is an excessively high mood (euphoria) or an abnormally irritable mood. To have bipolar I mania, your mood must last for a week or more (less time if the person has to go to the hospital). Along with the euphoria or irritability, you should have at least three or four of the following symptoms:

Inflated sense of self-importance (eg, may have grandiose delusions or overestimate abilities and talents)
Decreased need for sleep (eg, may go days without sleep and not feel tired)
Loud, rapid speech (eg, may talk nonstop)
Racing thoughts (eg, may abruptly jump from one subject to another)
Distractibility (eg, may not be able to screen out irrelevant details)
Agitation or restlessness (eg, may pace or hold multiple conversations at once)
Increase in goal-oriented activities (eg, may have an increased sex drive or become excessively and inappropriately social)
Unwise involvement in pleasurable but potentially risky activities (eg, may rack up significant debt, have sex with strangers, abuse drugs, or make rash investment decisions)

Treating Bipolar I Depression

Bipolar I depression is a medical condition that requires treatment, which helps many people feel better.

When you have bipolar I disorder, your doctor may recommend using a combination of treatment options. Some examples of these include:

Medication to help relieve symptoms
Counseling or therapy sessions to provide emotional support and help you learn to cope with the illness
Education about the illness and how to manage it
Therapeutic recreation to show how to handle stress and help find activities you enjoy
Support groups to allow you to give and receive support from others who have similar problems

To find out if you have bipolar I depression and learn more about what treatment options are best for you, talk to your healthcare professional.

Symbyax is approved for acute treatment of bipolar I depression in adults. Symbyax is not approved for the treatment of bipolar I mania.

Living With Bipolar I Depression

Many people with bipolar I disorder find their symptoms dramatically affect their life, whether it's a depressive phase or a manic phase.

The episodes associated with bipolar I depression can be overwhelming and painful. The episodes and emotional symptoms can affect your ability to function and cope with your daily life.

When symptoms become serious, it's time to take action. You should seek help and support from other people, a healthcare professional, a family member, or a friend. Share as much information as possible with these people. By asking for their opinions, they can help decide which treatment options will be most helpful.

Remember that the road to getting better has many turns. By asking for help you can learn more about your unique symptoms, how to manage them, and how you can best take care of yourself.

Symbyax is approved for acute treatment of bipolar I depression in adults. Symbyax is not approved for the treatment of bipolar I mania.